Discovery of a potential new therapeutic target for cancer treatment
A Biological & Medical Sciences project
I am coming to the end of my PhD, which has yielded some very interesting results. We have identfied a novel gene which has the potential to be a therapeutic target for anti-angiogenic cancer treatment. I am currently writing my thesis up and we have submitted the research to a high ranking journal. However, my funding has run out, meaning that I will be unable to respond to any reviewers comments. Any funding help here will mean I am able to pay rent, while I finish off my project!
This research has been conducted using zebrafish to study the function of the gene and preliminary data suggests that it plays a similar role in human cell culture. This is an exciting project which has the potential to help people in the future.
|Academic Institution:||University of Sheffield|
|User Profile:||Aaron Savage|
What is your motivation for doing a PhD?
I have always been hungry for an academic challenge and doing a PhD has been a fantastic experience. Being able to publish my findings will be very exciting.
Why did you choose your research topic/title
I have always been interested in developmental biology and how we can apply knowledge leanred during development to disease.
I have presented this work at national and international conferences. I have been awarded prizes for my presentations.
What difference will this research make in your life and the lives of others?
My research uses the zebrafish to study the develoment of blood vessels (angiogenesis), looking in particular at how cell signals interact, via a previously uncharacterised gene. The insights gained from this study have been tested in human cell culture and similar effects have been observed, making this gene a potential therapeutic target for anti-angiogenesis treatment in cancer.